Penicillin/ampicillin efficacy among children with severe pneumonia due to penicillin-resistant pneumococcus (MIC=4 μg ml−1)
نویسندگان
چکیده
منابع مشابه
Penicillin resistant pneumococcus.
Resistance to other antimicrobial agents and chloramphenicol has also been reported. 4,5 Multiple resistant strains have been responsible for infection with a high mortality rate. 5 To our knowledge, isolation of penicillin resistant pneumococci has not been documented in this region. We report the isolation of a penicillin resistant strain from the throat of an eleven-month old baby boy and th...
متن کاملPenicillin-resistant pneumococcus and risk of treatment failure in pneumonia.
OBJECTIVE To determine whether the presence of in vitro penicillin-resistant Streptococcus pneumoniae increases the risk of clinical failure in children hospitalised with severe pneumonia and treated with penicillin/ampicillin. DESIGN Multicentre, prospective, observational study. SETTING 12 tertiary-care centres in three countries in Latin America. PATIENTS 240 children aged 3-59 months,...
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Lobar pneumonia models were established in rats by intratracheal inoculation of either penicillin-susceptible (immunocompetent model) or penicillin-resistant (immunocompetent and neutropenic models) Streptococcus pneumoniae. Untreated animals maintained a relatively high bacterial load in the lungs but only occasionally developed bacteraemia or pleurisy. The infection was rarely fatal in immuno...
متن کاملMeningitis due to mixed infection with penicillin-resistant and penicillin-susceptible strains of Streptococcus pneumoniae.
Streptococcus pneumoniae is the major cause of bacterial meningitis. We report a case of meningitis due to a mixed infection with two distinct strains of S. pneumoniae: one penicillin-resistant strain of serotype 9V and one penicillin-susceptible strain of serotype 7. The two strains exhibited different pulsed-field gel electrophoresis profiles.
متن کاملHighly penicillin-resistant multidrug-resistant pneumococcus-like strains colonizing children in Oeiras, Portugal: genomic characteristics and implications for surveillance.
While performing surveillance studies in Oeiras, Portugal, designed to describe the impact of pneumococcal conjugate vaccine on colonization, we observed an increase from 0.7% in 2003 to 5% in 2006 in the prevalence of penicillin resistance (MIC of 2 to 6 mg/liter) among presumptively identified pneumococcal isolates. Although 15 of the 22 penicillin-resistant isolates obtained in 2006 were opt...
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ژورنال
عنوان ژورنال: Journal of Medical Microbiology
سال: 2009
ISSN: 0022-2615,1473-5644
DOI: 10.1099/jmm.0.007765-0